Our Team

  • Cornelius Gati, Dr. rer. nat.

    Assistant Professor

    gati (at) usc.edu

    ORCID ID: 0000-0003-3693-7009

    Google Scholar: Citations

    BlueSky: @gati.bsky.social

    Twitter: @CorneliusGati

    CV: CV-Gati

    Cornelius performed his PhD work in the group of Henry Chapman at the Center for Free-Electron Laser Science at DESY, Germany. The focus of his PhD was the development of the technique of serial crystallography at modern X-ray light sources, namely third generation synchrotrons and X-ray Free-Electron Lasers.

    After his PhD he moved on to do a PostDoc in the lab of Sjors Scheres at the MRC Laboratory of Molecular Biology in Cambridge, UK, where he learnt everything about single particle cryoEM. From 2018-2020 he was an independent group leader at SLAC National lab and the Stanford School of Medicine.

    In 2021, Cornelius joined USC as an Assistant Professor for Molecular and Cellular Biosciences. He also holds a joint appointment with the Departments of Chemistry, Pharmacy and Pharmacological Sciences, and Quantitative and Computational Biology.

  • Gye Won Han

    Gye Won Han, PhD

    Senior Staff Scientist

    Co-Director, Structural Biology Core

    gyewon.han (at) usc.edu

    Dr. Gye Won Han received her B.S. and M.S. in Chemistry from Ewha Womans University in Seoul, South Korea, and trained in Crystallography at the University of Pittsburgh, where she earned her Ph.D.

    She conducted postdoctoral research at UC San Diego and UCLA before joining The Scripps Research Institute, where she served as a Scientific Associate at the Joint Center for Structural Genomics (JCSG), working on high-throughput structure determination of soluble proteins, and later as a Staff Scientist in the GPCR Network, focusing on membrane protein structures. In 2015, she joined the Bridge Institute at the University of Southern California, where she has served as Co-Director of the Structural Biology Core (SBC) since 2019.

    Dr. Han specializes in X-ray crystallography and cryo-electron microscopy, with a focus on the structure determination and refinement of membrane proteins. She has co-authored over 150 peer-reviewed publications and is named a Highly Cited Researcher by Clarivate Analytics.

  • Aaliyah Tyson

    Graduate Student - Chemistry

    ast_803 (at) usc.edu

    Twitter: @803Ast

    Aaliyah obtained a B.S. in Biochemistry from Loyola Marymount University in 2022. During her time at Loyola Marymount University she joined the group of David Moffet to study protein aggregation in the context of type 2 diabetes. In his lab, she participated in the lab’s efforts of screening  molecules to identify inhibitors of IAPP. Upon completing her undergraduate studies in 2023, she joined the Chemistry program at USC and subsequently the Gati lab. In the Gati lab she will complete her graduate research using cryoEM to investigate GPCR structure at the atomic scale to gain insight on the connection between their interactions with ligands and signaling partners and the pharmacological properties of these receptors.

  • Zixin Zhang

    Graduate Student - PIBBS

    zzhang96 (at) usc.edu

    Zixin earned his B.S. in Biochemistry from UCLA in 2020 and his M.H.S. in Biochemistry from Johns Hopkins University in 2021. His undergraduate research focused on elucidating interactions between actin and actin-binding proteins. During his graduate training at Johns Hopkins, Zixin investigated mechanisms underlying the pathogenesis of leukemia and inflammatory bowel disease, developing a strong interest in immune signaling pathways. In 2023, he joined the Medical Biophysics Program under PIBBS at the USC Keck School of Medicine. His graduate research will employ cryoEM to investigate the structural and pharmacological basis of complement receptor signaling to better understand how ligand engagement and downstream signaling partners drive immune responses.

  • Sayuri Pacheco, PhD

    PostDoc

    sayuripa (at) usc.edu

    Sayuri obtained her B.S in Biochemistry at California State University Northridge. As an undergraduate she worked in Dr. Ravinder Abrol's lab where she learned to apply molecular dynamics simulations to understand chaperone protein activation. She completed her PhD at Keck School of Medicine of USC in the lab of Dr. Ansgar Siemer. At USC her work focused on elucidating the highly flexible domains of alpha-synuclein, an amyloid fibril and hallmark of Parkinson's disease, using solid-state NMR, EPR, and molecular dynamics simulations. In the Gati lab, she hopes to learn and apply cryoEM to understand GPCR pharmacology.

  • Jeppe Nielsen, PhD

    PostDoc

    jcn_662 (at) usc.edu

    Joining May 2026 from University of Copenhagen, Denmark.

  • Zhangsong Wu, PhD

    Postdoc

    Joining soon from Chinese University of Hong Kong, Shenzhen, China.

  • Foram Patel

    Undergraduate researcher

    forampat (at) usc.edu

    Foram is a second-year undergraduate student at the University of Southern California, majoring in Biochemistry on the Pre-Medicine track. She is interested in exploring how biochemical and structural approaches can be used to better understand protein function and signaling in human health and disease.

  • Lab alumni

    Saif Khan (2021-2025, graduate student), now Lead Researcher in Babu Lab - St. Jude’s Children’s Research Hospital

    Jaskaran Singh (2024-2025, undergraduate researcher)

    Ravi Yadav (2022-2025, PostDoc), now PostDoc in Mchaourab Lab - Vanderbilt University

    Omar Salah (2023-2024, undergraduate researcher), now graduate student at CalTech

    Anthony Chen (2022-2023, undergraduate researcher), now graduate student at Taiwan International Graduate Program (TIGP)

    Tristan Mitchell (2022-2024, undergraduate researcher), now medical student at University of Hawai’i

    Zenia Motiwala (2021-2024, PostDoc), now Senior Scientist at Amgen

    Nanda Aduri (2019-2022, PostDoc), now Senior Scientist at The Janssen Pharmaceutical Companies of Johnson & Johnson

    Xinyu Xiang (2018, undergraduate researcher), now graduate student at Stanford University

    Jesse Coe (2018-2020, PostDoc), now Senior Scientist at KBI Biopharma